Cymbalta is manufactured by Eli Lilly and Troupe in Indianapolis , Ind.I have had chronic pain/numbness/tingling sensations in the left position of my face for over 15 years. Lester M. The Food and Drug Administration (FDA) announced the blessing of Cymbalta (duloxetine hydrochloride) capsules for the management of the pain associated with diabetic peripheral neuropathy. This happened in only five days of one 30mg birth control pill a day. Neurontin didn’t solve anything. Although the mechanism of action is unknown, patients treated with Cymbalta reported a greater drop-off in pain compared to placebo. Within 24 hours I noticed a significant easing of physical pain sensations in the area of concern, and I have reduced my pain killer intake by 50%, and volition cut it down to zero in another week to ten days. This is the first drug specifically approved for this suggestion. “Diabetes affect millions of Americans,” said Dr. A miracle for me. In some cases, patients knowledgeable dizziness and hot flashes. Diabetic peripheral neuropathy can manifest in a variety of ways but is usually characterized by burning, tingling, and numbing sensations first part or section of something in the feet, and later affecting the legs and/or hands. In comparison, 31 percent of patients treated with placebo reported this size of sustained pain reduction. “With this new treatment we will hopefully be capable to help relieve the pain associated with this terrible disease.” Diabetic peripheral neuropathy is a trouble associated with long standing diabetes or poor glucose control. Crawford, Acting FDA Commissioner. The state of being certain that adverse effects will not be caused and effectiveness of Cymbalta were established in two randomized, controlled studies of approximately 1074 patients. I tried Neurontin for 5 months but it made me sluggish, indolent, and depressed. The most commonly reported side effects were nausea, somnolence, dizziness, decreased craving, and constipation. Peripheral neuropathy is the most common complication of diabetes mellitus, affecting up to 62% of Americans with diabetes.