Cymbalta Might Ease Chemo-Linked Pain

Nicholas Vogelzang, who moderated the printing press briefing, said he sees far too much neuropathy in his patients, many of whom receive platinum-based chemotherapy.I used Cymbalta for a yr. They were randomly assigned to receive either a half-dose of Cymbalta starting at 30 milligrams (mg) per day for the initial week, then the full, 60-mg dose for another four weeks; or a placebo birth control pill for five weeks.According to Smith, Cymbalta is thought to help ease neuropathy by altering levels of grey matter neurotransmitters linked to nerve function. After that, slowly it came rear until I asked to be taken off. In the first few days I had pounding of my heart which was so bad I never slept all dark. The first 8 months were great in alleviating my all-over pain, which is why I was taking it. The findings were to be formally presented Monday.One expert was also encouraged by the findings.”Patients undergoing chemotherapy have got to face a multitude of changes, both physically and mentally, and improving their degree or grade of excellence of life during this phase of their lives is of utmost importance,” said Dr. Smith added that “33 percentage of patients in the duloxetine group had at least a 30 percent decrease in pain and 21 percentage of patients had at least a 50 percent decrease in pain” — numbers much higher than those on the placebo birth control pill.Patients taking Cymbalta also “had a greater decrease in the amount that physical pain interfered with some very important things — with applying to most members of a category activity, with movement, walking, normal work, relations with people, slumber and enjoyment of life,” Smith said.Still, not everyone in the study gained a welfare and some patients actually experienced an increase in tingling/numbness during the legal proceedings. Stephanie Bernik, chief of surgical oncology at Lenox Hill Hospital in New York urban center. “It is extremely exciting that there is now a drug we can offer that can trim this terrible side effect and make chemotherapy more tolerable.”Chemotherapy-induced peripheral neuropathy involves a tingling and numbness in the hands and feet, and is a average or ordinary or usual side effect of chemotherapies such as the platinum-based medications or taxanes (drugs such as Taxol or Taxotere). It is estimated that up to 30 percentage of patients who receive these medications experience neuropathy, and the side effect is a contributing anything that contributes causally to a result to patients dropping treatment.In the worst cases, “some patients brave this painful neuropathy for months and possibly as long as years following completion of therapy,” Smith said. After weaning off, playing card in the major suit of hearts pounding & insomnia started again. However, this was less frequent for those on Cymbalta (11 percentage) than on a placebo (28 percent), the authors said.Cymbalta may come with position effects of its own, notably fatigue, and 11 percent of patients on Cymbalta reported moderate to severe fatigue versus 3 percentage of those taking the dummy pill.Smith said her team is now working on trying to ” forebode who might respond [to Cymbalta] so that we can target the use of this drug to the people who are mostly plausible to benefit.”Another oncologist said he was heartened by these initial results.”It’s consistent with fact or reality there are not many great treatments for neuropathy, something that is a common position effect of some of the chemotherapy medications that we use for the most common cancers: respiratory organ, colon and breast,” said Dr. The drug is already used to treat diabetic peripheral neuropathy, the room used for reading and writing and studying noted.The study found that more patients taking Cymbalta were more plausible to report a decrease in neuropathic symptoms compared to those on the placebo. National Malignant disease Institute, involved 231 cancer patients who had developed peripheral neuropathy after taking either the platinum-based malignant disease drug oxaliplatin or the taxane paclitaxel (Taxol). Cancer patients on certain chemotherapies often accumulation of knowledge or skill a painful tingling in their extremities called peripheral neuropathy, and a new study suggests the antidepressant Cymbalta may be the initial treatment to work against the condition.In the small study, 59 percent of patients who’d knowledgeable peripheral neuropathy said that they gained relief after taking Cymbalta (duloxetine), compared to 39 percentage who took a “dummy” pill.Taking Cymbalta daily “decreases chronic chemotherapy-induced neuropathy and physical pain severity in the majority of patients who take it and it improves function and quality of life,” said room used for reading and writing and studying author Ellen Lavoie Smith, an assistant professor at the University of Michigan’s Schoolhouse of Nursing. MD put me on another blood pressure pill which helped after upping the dosage a duo times.